IEEE Sección Ecuador y el Capítulo Técnico de Ingeniería en Medicina y Biología tienen el agrado de invitar a la serie de webinars Organs-on-a-chip y Microfluidics.
Los webinars no tienen costo, serán moderados por el Dr. Jorge Uquillas de YachayTech y tendrán una duración de una hora.
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|Organs-on-a-Chip: Engineering biomimetic hepatic platforms for drug testing
Solange Massa, MD, PhD (c)
Organs-on-a-chip are microfluidic devices that integrate cell culture and scaffolding to mimic human organ functions in vitro. These platforms will allow early toxicity testing to reduce the use of animal testing while greatly diminishing the costs of drug discovery and development.
28 de Enero, 2015. 9:00 GMT-5
Acerca del Expositor
Solange Massa holds an M.D. from the Universidad Austral (Argentina) and is Ph.D. Candidate from the Universidad de los Andes (Chile). In 2013 she was appointed Assistant Professor at the San Sebastian Medical School (Chile) and before that, Visiting Professor at the same institution. She did collaborative research with the Nanobiotechnology Lab of the Universidad de Chile and Neurobiology Lab at Universidad de los Andes (Chile). Currently she is a Research Fellow at Khademhosseini Lab (Harvard-MIT Health Sciences & Technology, Brigham and Women's Hopsital, Harvard Medical School). Here she develops body-on-a-chip platforms for metabolic/disease marker evaluation and drug toxicity screening.
|Organs-on-a-Chip: Engineering biomimetic cardiovascular platforms
João Ribas, MSc, PhD (c)
Organs-on-a-chip hold the promise of revolutionizing the drug discovery pipeline as a valuable tool with high predictive value. In this lecture we will summarize the current strategies developed to mimic the cardiovascular system, focusing mainly on heart and blood vessel-on-a-chip platforms. We will explore both the chip biodesign approach and the key biological aspects that support this technology.
4 de Febrero, 2015. 9:00 GMT-5
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João Ribas holds a Master of Science in Molecular and Cellular Biology from the University of Coimbra, in collaboration with the Institute for Molecular and Cell Biology (IBMC), University of Porto. He worked as a Research Assistant at the Institute for Biomedical Engineering (Univ. Porto) unveiling the interplay between central and peripheral nervous system and bone regeneration. He is a recipient of a highly competitive PhD Program fellowship from the University of Coimbra in Experimental Biology and Biomedicine. Since December 2012, João has been developing his PhD research at Khademhosseini Lab on vasculature on a chip, and is a Research Fellow at Harvard Medical School and Visiting PhD Student at Harvard-MIT Health Sciences & Technology and Brigham and Women's Hospital.
|Microfluidics and its applications on automated biosystems: biomechanical and bioengineered considerations
Julio César Aleman
This webinar will explore work on organ-on-a-chip platforms with hepatic, and cardiac elements integrated using a blood vessel-like system for ex-vivo drug detection system in humans. Based on highly reliable automated systems. We will go over current designs, fluidic dynamic applications, and fabrication techniques of prototypes that are being currently developed.
11 de Febrero, 2015. 9:00 GMT-5
Acerca del Expositor
Julio Aleman holds BS degrees in biochemistry, and microbiology at Universidad Del Vallde de Guatemala. His research experience starts with kidney and heart transplant studies, Crohn's disease immunology studies and translational research at the James Graham Brown Cancer Center Clinical and Translational Research University of Louisville. Rapid Rhabdomyosarcoma FISH-based detection system studies at Dana Farber Cancer Institute. Stem cell development for human islet development and type 1 diabetes surgical treatment in translational research at the Diabetes Research Institute of the University of Miami, Miller School of Medicine. His main interest is applied and translational research in the field of regenerative medicine, especially in scaffolds, and kidney tissue engineering applications. He is currently a researcher at Harvard-MIT Health Science and Technology Department, and the Brigham and Women's Hospital at Harvard Medical School where he develops microfluidic biosystems to develop organ-on-a-chip and human-on-a-chip platforms.
|Innovative strategies for the development of new bio-interface systems
Mattia Comotto, MSc, PhD (c)
In the past few years, biomedical engineering has focus on the development of new devices that can interact and interface directly with living tissue, e.g. wounds, muscular tissue, and nerve fibers. Conventional technologies typically involved small numbers of points of contact, flat electrodes attached to the skin with adhesive tape, and conductive gels to minimize impedance upon contact with skin and tissue. To address these issues, an important goal of the new class of electronics is to achieve high-performance systems that actively interact with the biological tissue. Therefore, we aim to develop implantable devices that can resorbed by the body, which would lead to eliminate implant removal surgeries.
In order to have higher contact area and adhesion to the tissue, strong Van Der Waals interactions are necessary. For this reason, in this Webinar we will focus on flexible materials designed to match the physical properties of the biological tissue. Bio-interface systems, with ultrathin electronics and bioresorbable substrates allow obtaining a highly conformal coverage. Furthermore, the possibility to integrate these systems with temperature, pH, strain, and electrophysiological sensors, as well as on-demand drug release systems, solar cells, and wireless coil for the power supply, represent a key point in the development of a new generation of medial devices. Some of these devices are implantable devices, smart wound dressing and epidermal flexible sensors with implications not only in medicine, but also in consumer electronics, where degradability avoid all the issues related to the waste streams (recycling and practical difficulties in device collection/recovery).
Acerca del Expositor
Mattia Comotto is a PhD candidate in Chemical Engineering at University of Genoa-Italy, where he got his Master degree in Chemical Sciences. He is currently a researcher at Harvard-MIT Health Science and Technology Department, and the Brigham and Women's Hospital at Harvard Medical School where he works on his doctoral dissertation. He has experience in extraction, recovery and purification of antioxidant compounds from agricultural and food wastes and his thesis involve the application of these compounds in the biomaterials field. Specifically, his research interests span different areas like the development of a smart dressing for chronic wounds management, stretchable electronics, and the development of functionalized vascular prosthesis.