Did you get your genome sequenced for Christmas?

The kit for sequencing your genome. Credit: 23andMe

Indeed, did you receive as Christmas present the kit for sequencing your genome? May be not, but many thousands of people did. And this is amazing!

There are several companies that are offering private people the possibility of sequencing their genome (23andMe, Omegabioservice, Illumina, Cegat, OriGene, Eurofins Genomics, AncestryDNA, …) with prices varying from 59$ (AncestryDNA) up  to 999€ (Cegat) and much more (Illumina).

The price variation is related to the amount of the genome that is actually sequenced. As an example, AncestryDNA has the goal of finding out your origin, where your ancestors came from and to that effect only few parts of the genome are relevant, hence the low 79$ price. At the other end Illumina can provide you with a complete sequencing and the price goes up over 1,000$.

Anyhow, what I think is amazing is the drop in price. Less than 20 years ago the sequencing of the first genome took 7 years and required several billion $. Today you can get a genome sequenced in days (with part of that time used for sending the specimen and receiving the result..) at a cost that is less than one millionth of that.

The world map provided by AncestryDNA shows the roots of your genome, the locations that have a match with your sequencing, basically telling you where your ancestors lived. The color code represents the strength of the relation. Credit: AncestryDNA

The kit shown in the figure is from 23andMe, it is available in the US and a few European Countries. In other Countries you can get similar service from different companies. The process is quite easy. You have to part from a few of your hair and send them to the company for DNA extraction and sequencing (in some cases they ask for your spit). In a few weeks (most of the time within two weeks) you get the result in form of a map showing your ancestry origin plus other information.

The sequencing provided by most of these companies is mostly for fun (and it is fun to look back into your past, isn’t it?). More expensive, and complete, sequencing like the one provided by Illumina   can be used for medical investigation. However, as Time as pointed out in an article just before Christmas do not expect your genome sequencing to tell you how long is your life expectation, whether you are likely to get cancer and so on. So far our knowledge on the “implication” of the genome are quite limited.  What we can already do in health care is to look at the genome once you have been diagnosed a specific ailment and look for specific genes that would make one cure more effective than another (this has become normal practice in some form of cancer cure).

About Roberto Saracco

Roberto Saracco fell in love with technology and its implications long time ago. His background is in math and computer science. Until April 2017 he led the EIT Digital Italian Node and then was head of the Industrial Doctoral School of EIT Digital up to September 2018. Previously, up to December 2011 he was the Director of the Telecom Italia Future Centre in Venice, looking at the interplay of technology evolution, economics and society. At the turn of the century he led a World Bank-Infodev project to stimulate entrepreneurship in Latin America. He is a senior member of IEEE where he leads the New Initiative Committee and co-chairs the Digital Reality Initiative. He is a member of the IEEE in 2050 Ad Hoc Committee. He teaches a Master course on Technology Forecasting and Market impact at the University of Trento. He has published over 100 papers in journals and magazines and 14 books.