IEEE Transactions on Nanotechnology



The IEEE Transactions on Nanotechnology (TNANO) publishes novel and important results in engineering at the nanoscale.  

Article in focus: October 2016

From the September 2016 issue of IEEE Transactions on Nanotechnology

Halloysite Clay Nanotubes as Carriers for Curcumin: Characterization and Application

by Chiara Dionisi ; Nemany Hanafy ; Concetta Nobile ; Maria Luisa De Giorgi ; Ross Rinaldi ; Sergio Casciaro ; Yuri M. Lvov ; Stefano Leporatti
T-NANO, Vol. 15, Issue 5, pp. 720 – 724, September 2016.


Abstract: Halloysite is a nanostructured clay mineral with hollow tubular structure, which has recently found an important role as delivery system for drugs or other active molecules. One of these is curcumin, main constituent in the rhizome of the plant Curcuma Longa, with a series of useful pharmacological activities, hindered by its poor bioavalaibility and solubility in water. In this study, Halloysite clay nanotubes (HNTs) were characterized in terms of both structure and biocompatibility and they were used for curcumin delivery to cancer cells. The performed 3-(4, 5-dimethythiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay showed that HNTs have a high biocompatibility, also when coated with polymers, while curcumin is highly toxic for cancer cells. The release kinetics of curcumin from HNTs was investigated by the dialysis bag method, showing a slow and constant release of the drug, which can be further controlled by adding layers of polyelectrolytes to the external surface of the tubes. Successful polymer coating was followed by Zeta potential. The Trypan Blue assay showed a cytotoxic effect of loaded HNTs, proportional to the concentration of tubes and the incubation time. Successful HNTs uptake by breast cancer cells was demonstrated by Confocal Laser Scanning Microscopy images. All results indicate that HNTs are a promising carriers for polyphenol delivery and release.


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Message from the Editor-In-Chief

by Fabrizio Lombardi


On December 31 2015, I completed the first year of my term as Editor-In-Chief (EIC); as you will read further in this editorial, I am pleased to report that the IEEE Transactions on Nanotechnology (TNANO) continues to strengthen its reputation and consolidate its role as the flagship Transactions of the IEEE Nanotechnology Council (NTC). 2015 has been an outstanding year for TNANO; Manuscript Central Scholar 1 reports the following very impressive statistics for the 2015 calendar year:

Number of submitted original papers: 647
Number of revised-and-resubmitted papers: 99
Total number of papers received: 746
Acceptance rate: 30.4%
Rejection rate: 51.6%
Revise-and-resubmit rate: 18%

All the above numbers are the absolute best in quantitative and qualitative terms (such as for the highest selectivity) in the 14 years of existence of TNANO and reflect the steady and continued growth in terms of quality and quantity of this periodical. (continue to read)

Information about TNANO

TNANO focuses on nanoscale devices, systems, materials and applications, and on their underlying science. It is an interdisciplinary journal that covers all areas of nanotechnology. The hardcopy version is published bi-monthly, but accepted papers are published on the web as soon as they are submitted in final form. TNANO is a publication of the IEEE Nanotechnology Council.

TNANO is a Hybrid Journal, which means that it allows either:

  • Traditional manuscript submission
  • Open Access (author-pays OA) manuscript submission at a discounted rate

 TNANO publishes Research Letters, Regular Papers, and Correspondence Items. Research Letters must not exceed three printed pages. They are subject to the same thorough review process as Regular Papers, but receive priority treatment. A Research Letter that is accepted without major revisions is expected to be published on the web within 4 to 6 weeks of its initial submission.

Areas covered by TNANO include, but are not limited to:

  • Nano and Molecular Electronics
  • Circuits and Architectures
  • Nanomagnetism and Spintronics
  • Nano-Optics, Nano-Optoelectronics and Nanophotonics
  • Nanorobotics and Nanoassembly
  • Nanosensors and Nanoactuators
  • Nanomechanics and Nanoelectromechanical Systems
  • Nanobiotechnology and Nanomedicine
  • Nanofabrication and Nanolithography
  • Nanometrology and Characterization
  • Computational Nanotechnology

Additional information on these is found here.