IEEE Transactions on Nanotechnology
IEEE

Home

NTC-logo300x80.jpg 

The IEEE Transactions on Nanotechnology (TNANO) publishes novel and important results in engineering at the nanoscale.  


Article in focus: January 2016

From the January 2016 issue of IEEE Transactions on Nanotechnology

Novel Nano-Device to Measure Voltage-Driven Membrane Transporter Activity

by Rikiya Watanabe, Naoki Soga, and Hiroyuki Noji T-NANO, Vol. 15, Issue 1, pp. 70 – 73, January 2016.

 

7321075-fig-1-large
ALBiC with nano-sized electrode (el-ALBiC). (a) A bright-field image of the through-hole structures on a fabricated nano-device. (b) Schematic illustration of el-ALBiC that displays through-hole structures on a double layer of fluororesin (h = 500 nm) and Au (h = 500 nm). Individual orifices on through-hole structures are sealed with lipid-bilayer membranes.
 

Abstract: The use of an arrayed lipid bilayer chamber system (ALBiC) enables highly sensitive quantitative analysis of membrane transporter activity, a major target of pharmaceutical research. Although membrane voltage is one of the main driving forces of transporters, the versatility of ALBiC is limited to transporter assays in the absence of membrane voltage, owing to technical limitations with voltage modulation. Here, we report a novel nano-device based on ALBiC (el-ALBiC) containing sub-million lipid bilayer chambers, each equipped with nano-sized electrodes. Since the nano-sized electrodes enable quantitative modulation of membrane voltage, the el-ALBiC is capable of performing highly sensitive detection of the voltage-driven membrane transporter activity. Thus, the novel nano-device el-ALBiC extends the versatility of ALBiC and has potential for further analytical and pharmacological applications, such as drug screening.

 


Message from the Editor-In-Chief

by Fabrizio Lombardi

 

On December 31 2015, I completed the first year of my term as Editor-In-Chief (EIC); as you will read further in this editorial, I am pleased to report that the IEEE Transactions on Nanotechnology (TNANO) continues to strengthen its reputation and consolidate its role as the flagship Transactions of the IEEE Nanotechnology Council (NTC). 2015 has been an outstanding year for TNANO; Manuscript Central Scholar 1 reports the following very impressive statistics for the 2015 calendar year:

Number of submitted original papers: 647
Number of revised-and-resubmitted papers: 99
Total number of papers received: 746
Acceptance rate: 30.4%
Rejection rate: 51.6%
Revise-and-resubmit rate: 18%

All the above numbers are the absolute best in quantitative and qualitative terms (such as for the highest selectivity) in the 14 years of existence of TNANO and reflect the steady and continued growth in terms of quality and quantity of this periodical. (continue to read)


Information about TNANO

TNANO focuses on nanoscale devices, systems, materials and applications, and on their underlying science. It is an interdisciplinary journal that covers all areas of nanotechnology. The hardcopy version is published bi-monthly, but accepted papers are published on the web as soon as they are submitted in final form. TNANO is a publication of the IEEE Nanotechnology Council.

TNANO is a Hybrid Journal, which means that it allows either:

  • Traditional manuscript submission
  • Open Access (author-pays OA) manuscript submission at a discounted rate


 TNANO publishes Research Letters, Regular Papers, and Correspondence Items. Research Letters must not exceed three printed pages. They are subject to the same thorough review process as Regular Papers, but receive priority treatment. A Research Letter that is accepted without major revisions is expected to be published on the web within 4 to 6 weeks of its initial submission.


Areas covered by TNANO include, but are not limited to:

  • Nano and Molecular Electronics
  • Circuits and Architectures
  • Nanomagnetism and Spintronics
  • Nano-Optics, Nano-Optoelectronics and Nanophotonics
  • Nanorobotics and Nanoassembly
  • Nanosensors and Nanoactuators
  • Nanomechanics and Nanoelectromechanical Systems
  • Nanobiotechnology and Nanomedicine
  • Nanofabrication and Nanolithography
  • Nanometrology and Characterization
  • Computational Nanotechnology


Additional information on these is found here.