IEEE Transactions on Nanotechnology
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Archive for October, 2016

TNANO Article in focus: October 2016

Wednesday, October 19th, 2016

From the September 2016 issue of IEEE Transactions on Nanotechnology

Halloysite Clay Nanotubes as Carriers for Curcumin: Characterization and Application

by Chiara Dionisi ; Nemany Hanafy ; Concetta Nobile ; Maria Luisa De Giorgi ; Ross Rinaldi ; Sergio Casciaro ; Yuri M. Lvov ; Stefano Leporatti
T-NANO, Vol. 15, Issue 5, pp. 720 – 724, September 2016.

 
Immagine

Abstract: Halloysite is a nanostructured clay mineral with hollow tubular structure, which has recently found an important role as delivery system for drugs or other active molecules. One of these is curcumin, main constituent in the rhizome of the plant Curcuma Longa, with a series of useful pharmacological activities, hindered by its poor bioavalaibility and solubility in water. In this study, Halloysite clay nanotubes (HNTs) were characterized in terms of both structure and biocompatibility and they were used for curcumin delivery to cancer cells. The performed 3-(4, 5-dimethythiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay showed that HNTs have a high biocompatibility, also when coated with polymers, while curcumin is highly toxic for cancer cells. The release kinetics of curcumin from HNTs was investigated by the dialysis bag method, showing a slow and constant release of the drug, which can be further controlled by adding layers of polyelectrolytes to the external surface of the tubes. Successful polymer coating was followed by Zeta potential. The Trypan Blue assay showed a cytotoxic effect of loaded HNTs, proportional to the concentration of tubes and the incubation time. Successful HNTs uptake by breast cancer cells was demonstrated by Confocal Laser Scanning Microscopy images. All results indicate that HNTs are a promising carriers for polyphenol delivery and release.
 


Special Section on VLSI and Nanotech. Design Trends for Computing Innovations

Wednesday, October 5th, 2016

Joint Special Section on VLSI and Nanotechnology Design Trends for Computing Innovations

IEEE Transactions on Nanotechnology and IEEE Transactions on Emerging Topics in Computing seek original manuscripts for a Special Section tentatively scheduled to appear in the September 2017 issues.
The topics of interest for this special section include:

  • VLSI Design: Design of ASICs, microprocessors/micro-architectures, embedded processors, digital systems, NoC, interconnects, memories, and FPGAs.
  • VLSI Circuits: digital circuits, chaos/neural/fuzzy-logic circuits, high-speed/low-power circuits.
  • Low Power and Power Aware Design: Circuits, micro-architectural techniques, thermal estimation and optimization, power estimation methodologies, and CAD tools.
  • Computer-Aided Design (CAD): Hardware /software co-design, logic and behavioral synthesis, logic mapping, simulation and formal verification, layout (partitioning, placement, routing, floor planning, compaction), algorithms and complexity.
  • Testing, Reliability, Fault-Tolerance: Digital testing, design for testability and reliability, online testing techniques, static and dynamic defect- and fault-recoverability, and variation-aware design.
  • Emerging Technologies & Post-CMOS VLSI: Analysis, circuits and architectures, modeling, CAD tools and design methodologies for nanotechnologies, molecular electronics, quantum devices, biologically-inspired computing, spintronic technology, CNT, MTJ, NML, PCM, PMC, and sensor and sensor networks, etc.

Submitted articles must not have been previously published or currently submitted for journal publication elsewhere. An extended version of an article appearing in a conference proceedings (and in particular, GLSVLSI 2016) can be submitted provided that it has substantially new content w.r.t. to the original conference version. The conference paper must be cited in the main text and the cover letter must clearly describe the differences with the conference version and clearly identify the new contributions. As an author, you are responsible for understanding and adhering to the submission guidelines. Authors are invited to submit manuscripts focused on topics of computing directly to Transactions on Emerging Topics in Computing (TETC) at https://mc.manuscriptcentral.com/tetc-cs and papers focused on topics of nanoscale circuits and technology directly to Transactions on Nanotechnology (TNano) at https://mc.manuscriptcentral.com/tnano. Authors should be aware that papers can be published in TNano or TETC depending on the availability of space with the final allocation at the discretion of the Editor-in-Chief of the respective Transactions. Please address all correspondence regarding this Special Section to the Guest Editors (email: tpc.chairs@gmail.com).

Important Dates

  • Manuscript Submission: November 1, 2016.
  • First decision to authors: February 1, 2017.
  • Revision due (if necessary): April 1, 2017.
  • Final notification (acceptance/rejection): July 1, 2017.
  • Final manuscripts due: August 1, 2017.
  • Special section publication: September 2017.

Guest Editors

 

Laleh Behjat (University of Calgary)

Ayse Coskun (Boston University)

Jie Han (University of Alberta)

Martin Margala (University of Massachusetts Lowell)

The Call for Papers is available here