Title:
Effect of saline infusion on obstructive sleep apnea severity in men
Date:
Thursday, Nov 21, 2013 from 5:30-6:30pm
Location:
EITC E2-330, University of Manitoba
Speaker:
Azadeh Yadollahi, Ph.D.
Abstract:
Recently, we have shown that sedentary living leads to excess fluid retention in the legs during the day and to a shift of this fluid when recumbent at night into the neck or chest, narrowing the airway, increasing airway resistance and predisposing to sleep apnea. In this talk, I will:
- review the current evidence for the role of rostral fluid shift on the pathogenesis of obstructive sleep apnea.
- describe the pattern of fluid redistribution in various body segments in men and women while supine, and
- describe the effect of intravenous saline infusion during sleep on the severity of obstructive sleep apnea in healthy men.
Speaker Bio:
Azadeh Yadollahi received her Ph.D. degree in biomedical engineering from the University of Manitoba in 2011 and she is currently a Postdoctoral fellow in the Institute of Biomaterial and Biomedical Engineering at the University of Toronto and an affiliated research scientist at the Toronto’s University Health Network-Toronto Rehabilitation Institute (UHN-TRI). Her Ph.D. research was very productive and led to registering one patent, publishing ten journal papers and receiving two prestigious awards: Philips Young Investigator Award and NSERC Innovation Challenge Award. Her current research at University of Toronto and UHN-TRI builds up on this foundation, to investigate how fluid accumulation in various body segments affects the pathogenesis of sleep apnea.
